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¿Son dos semanas, el criterio de la duración óptima de la depresión mayor?


Angst, J; Hengartner, M P; Ajdacic-Gross, V; Roessler, W (2014). ¿Son dos semanas, el criterio de la duración óptima de la depresión mayor? Actas Españolas de Psiquiatría, 42(1):18-27.

Abstract

INTRODUCTION: A clinically useful diagnostic classification should identify most patients who are treated. To our surprise, DSM-IV criteria for major depressive episodes (MDE) detected fewer than 50% of a community sample (the Zurich study) who had received treatment for depression.1 Treated subjects often experience episodes lasting under 2 weeks, or with fewer symptoms than required for a DSM diagnosis. METHODS: Our paper focuses on the validity and clinical relevance of the length of depressive syndromes, defined by the presence of 5 or more of 9 diagnostic symptoms (DSM-IV). RESULTS: We found depressive syndromes lasting under 2 weeks to be highly prevalent, and those lasting 4+ days to have equal validity (family history, age of onset, course) and treatment rates to episodes of 2-4 weeks. CONCLUSIONS: The 2-week criterion for MDE would appear questionable. Our results need confirmation by larger epidemiological studies.

INTRODUCTION: A clinically useful diagnostic classification should identify most patients who are treated. To our surprise, DSM-IV criteria for major depressive episodes (MDE) detected fewer than 50% of a community sample (the Zurich study) who had received treatment for depression.1 Treated subjects often experience episodes lasting under 2 weeks, or with fewer symptoms than required for a DSM diagnosis. METHODS: Our paper focuses on the validity and clinical relevance of the length of depressive syndromes, defined by the presence of 5 or more of 9 diagnostic symptoms (DSM-IV). RESULTS: We found depressive syndromes lasting under 2 weeks to be highly prevalent, and those lasting 4+ days to have equal validity (family history, age of onset, course) and treatment rates to episodes of 2-4 weeks. CONCLUSIONS: The 2-week criterion for MDE would appear questionable. Our results need confirmation by larger epidemiological studies.

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3 citations in Web of Science®
3 citations in Scopus®
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Additional indexing

Other titles:Is two weeks the optimum duration criterion for major depression?
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Psychiatry, Psychotherapy, and Psychosomatics
Dewey Decimal Classification:610 Medicine & health
Language:Spanish
Date:2014
Deposited On:04 Dec 2014 07:54
Last Modified:05 Apr 2016 18:34
Publisher:Grupo Ars XXI de Comunicacion, SA
ISSN:1139-9287
PubMed ID:24504990
Permanent URL: https://doi.org/10.5167/uzh-101498

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