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Prätherapeutische Biomarker des Lungenkarzinoms unter besonderer Berücksichtigung der Bronchoskopie


Darwiche, K; Ozkan, F; Ting, S; Johnen, G; Brüning, T; Soltermann, A; Huber, L C; Christoph, D C; Freitag, L; Franzen, D (2014). Prätherapeutische Biomarker des Lungenkarzinoms unter besonderer Berücksichtigung der Bronchoskopie. Pneumologie (Stuttgart, Germany), 68(11):719-726.

Abstract

Molecular biomarkers are becoming increasingly significant in the workup of lung carcinoma patients. They assist in diagnosis, selecting the most adequate therapy and determining prognosis. Obtaining blood based biomarkers or volatile markers in exhaled breath may provide a less invasive method in the future. For the time being, bronchoscopy is still the method of choice to obtain specimen and assess tissue based biomarkers. The techniques how specimen are collected and processed for analysis are of paramount importance.

Molecular biomarkers are becoming increasingly significant in the workup of lung carcinoma patients. They assist in diagnosis, selecting the most adequate therapy and determining prognosis. Obtaining blood based biomarkers or volatile markers in exhaled breath may provide a less invasive method in the future. For the time being, bronchoscopy is still the method of choice to obtain specimen and assess tissue based biomarkers. The techniques how specimen are collected and processed for analysis are of paramount importance.

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Additional indexing

Other titles:Role of Pretherapeutic Biomarkers in Lung Cancer with Special Regards to Bronchoscopic Procedures
Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Surgical Pathology
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:November 2014
Deposited On:11 Dec 2014 10:32
Last Modified:05 Apr 2016 18:37
Publisher:Georg Thieme Verlag
ISSN:0934-8387
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1055/s-0034-1377299
PubMed ID:25003906
Permanent URL: https://doi.org/10.5167/uzh-102285

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