Hengartner, M O (1996). Programmed cell death in invertebrates. Current Opinion in Genetics & Development, 6(1):34-38.
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Genetic studies of programmed cell death in Caenorhabditis elegans and Drosophila melanogaster have led to the identification of several invertebrate cell death genes. In C. elegans, ced-3 and ced-4 function to kill cells, whereas ced-9 protects cells from death. In Drosophila, the genes reaper and hid act in parallel to promote cell death. Characterization of these genes has revealed that the process of programmed cell death is evolutionarily conserved and has shed light on the molecular nature of the apoptotic machinery.
|Item Type:||Journal Article, refereed|
|Communities & Collections:||07 Faculty of Science > Institute of Molecular Life Sciences|
|DDC:||570 Life sciences; biology|
|Date:||01 February 1996|
|Deposited On:||11 Feb 2008 13:20|
|Last Modified:||27 Nov 2013 18:28|
|Citations:||Web of Science®. Times Cited: 87|
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