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Matriderm versus Integra: a comparative experimental study


Schneider, J; Biedermann, T; Widmer, D; Montaño, I; Meuli, M; Reichmann, E; Schiestl, C (2009). Matriderm versus Integra: a comparative experimental study. Burns, 35(1):51-57.

Abstract

AIM: To compare engraftment rates and vascularisation in a rat model using either Integra Artificial Skin or Matriderm. METHODS: Matriderm and the dermal part of Integra were compared in a two-step procedure including matrix implantation and subsequent epidermal grafting. Neonatal rat epidermis was used as coverage to test for rapid and complete take. RESULTS: Efficiency and quality of vascularisation expressed by take rate of epidermis, and thickness of resulting neodermis, were identical for both matrices. CONCLUSION: This first comparison of Matriderm with Integra in a rat model revealed no major differences in engraftment rates or vascularisation.

Abstract

AIM: To compare engraftment rates and vascularisation in a rat model using either Integra Artificial Skin or Matriderm. METHODS: Matriderm and the dermal part of Integra were compared in a two-step procedure including matrix implantation and subsequent epidermal grafting. Neonatal rat epidermis was used as coverage to test for rapid and complete take. RESULTS: Efficiency and quality of vascularisation expressed by take rate of epidermis, and thickness of resulting neodermis, were identical for both matrices. CONCLUSION: This first comparison of Matriderm with Integra in a rat model revealed no major differences in engraftment rates or vascularisation.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2009
Deposited On:16 Jan 2009 13:23
Last Modified:05 Apr 2016 12:50
Publisher:Elsevier
ISSN:0305-4179
Publisher DOI:https://doi.org/10.1016/j.burns.2008.07.018
PubMed ID:18951720

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