UZH-Logo

Maintenance Infos

Out-of body experiences: cell-free cell death.


Hengartner, M O (1995). Out-of body experiences: cell-free cell death. BioEssays, 17(6):549-552.

Abstract

Apoptosis (programmed cell death) is an evolutionarily conserved cellular process, important for development and homeostasis. Most apoptotic cells share a common set of morphological and physiological characteristics that distinguish them from necrotic deaths. While genetic studies have indicated that these characteristic changes result from the activation of an endogenous 'suicide program', little is known about the nature of this program and the molecular events underlying these changes. Two recent papers describing cell-free extracts that reproduce several of the characteristic changes observed in apoptotic cells promise to make these phenomena accessible to biochemical analysis.

Apoptosis (programmed cell death) is an evolutionarily conserved cellular process, important for development and homeostasis. Most apoptotic cells share a common set of morphological and physiological characteristics that distinguish them from necrotic deaths. While genetic studies have indicated that these characteristic changes result from the activation of an endogenous 'suicide program', little is known about the nature of this program and the molecular events underlying these changes. Two recent papers describing cell-free extracts that reproduce several of the characteristic changes observed in apoptotic cells promise to make these phenomena accessible to biochemical analysis.

Citations

3 citations in Web of Science®
3 citations in Scopus®
Google Scholar™

Altmetrics

Additional indexing

Item Type:Journal Article, refereed
Communities & Collections:07 Faculty of Science > Institute of Molecular Life Sciences
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:1 June 1995
Deposited On:11 Feb 2008 12:20
Last Modified:05 Apr 2016 12:17
Publisher:Wiley-Blackwell
ISSN:0265-9247
Publisher DOI:10.1002/bies.950170612
PubMed ID:7575497

Download

Full text not available from this repository.View at publisher

TrendTerms

TrendTerms displays relevant terms of the abstract of this publication and related documents on a map. The terms and their relations were extracted from ZORA using word statistics. Their timelines are taken from ZORA as well. The bubble size of a term is proportional to the number of documents where the term occurs. Red, orange, yellow and green colors are used for terms that occur in the current document; red indicates high interlinkedness of a term with other terms, orange, yellow and green decreasing interlinkedness. Blue is used for terms that have a relation with the terms in this document, but occur in other documents.
You can navigate and zoom the map. Mouse-hovering a term displays its timeline, clicking it yields the associated documents.

Author Collaborations