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cDNA clones encoding human neurotrypsin have been isolated from a human fetal brain cDNA library using a PCR-amplified probe. The assembled cDNA sequence contains a 2625 bp open reading frame encoding a multidomain serine protease with an overall sequence identity of 82.5% to murine neurotrypsin. Surprisingly, the human neurotrypsin exhibits an additional scavenger receptor cysteine-rich repeat.
|Item Type:||Journal Article, refereed|
|Communities & Collections:||04 Faculty of Medicine > Institute of Biochemistry|
07 Faculty of Science > Institute of Biochemistry
|DDC:||570 Life sciences; biology|
|Uncontrolled Keywords:||Human neurotrypsin;, cDNA cloning|
|Date:||09 March 1998|
|Deposited On:||11 Feb 2008 13:20|
|Last Modified:||23 Nov 2012 16:38|
|WoS Citation Count:||21|
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