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Late ureteral obstruction after injection of dextranomer/hyaluronic acid copolymer


Christen, Samuel; Mendoza, Mario; Gobet, Rita; Bode, Peter; Weber, Daniel (2014). Late ureteral obstruction after injection of dextranomer/hyaluronic acid copolymer. Urology, 83(4):920-922.

Abstract

Various biological and artificial materials have been introduced for endoscopic treatment of vesicoureteral reflux. Over the past years, dextranomer combined with hyaluronic acid (Dx/Ha) has been established as the most commonly used tissue-augmenting substance for subureteral injection because of its biocompatibility. Nevertheless, the histopathologic analysis of failed Dx/Ha injections showed changes in consistency and volume of the deposit and granulomatous reactions of the adjacent tissue. We report a case of late-onset obstruction 2 years after the injection of Dx/Ha. In the current literature, this potential long-term complication is hardly mentioned.

Various biological and artificial materials have been introduced for endoscopic treatment of vesicoureteral reflux. Over the past years, dextranomer combined with hyaluronic acid (Dx/Ha) has been established as the most commonly used tissue-augmenting substance for subureteral injection because of its biocompatibility. Nevertheless, the histopathologic analysis of failed Dx/Ha injections showed changes in consistency and volume of the deposit and granulomatous reactions of the adjacent tissue. We report a case of late-onset obstruction 2 years after the injection of Dx/Ha. In the current literature, this potential long-term complication is hardly mentioned.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:April 2014
Deposited On:18 Feb 2015 17:04
Last Modified:05 Apr 2016 18:59
Publisher:Elsevier
ISSN:0090-4295
Publisher DOI:https://doi.org/10.1016/j.urology.2013.10.053
PubMed ID:24411212

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