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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-11009

Baerenfaller, K; Grossmann, J; Grobei, M A; Hull, R; Hirsch-Hoffmann, M; Yalovsky, S; Zimmermann, P; Grossniklaus, U; Gruissem, W; Baginsky, S (2008). Genome-scale proteomics reveals Arabidopsis thaliana gene models and proteome dynamics. Science, 320(5878):938-941.

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Abstract

We have assembled a proteome map for Arabidopsis thaliana from high-density, organ-specific proteome catalogs that we generated for different organs, developmental stages, and undifferentiated cultured cells. We matched 86,456 unique peptides to 13,029 proteins and provide expression evidence for 57 gene models that are not represented in the TAIR7 protein database. Analysis of the proteome identified organ-specific biomarkers and allowed us to compile an organ-specific set of proteotypic peptides for 4105 proteins to facilitate targeted quantitative proteomics surveys. Quantitative information for the identified proteins was used to establish correlations between transcript and protein accumulation in different plant organs. The Arabidopsis proteome map provides information about genome activity and proteome assembly and is available as a resource for plant systems biology.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Functional Genomics Center Zurich
07 Faculty of Science > Institute of Plant Biology
08 University Research Priority Programs > Systems Biology / Functional Genomics
08 University Research Priority Programs > Systems Biology / Functional Genomics
DDC:570 Life sciences; biology
580 Plants (Botany)
610 Medicine & health
Language:English
Date:2008
Deposited On:07 Feb 2009 15:43
Last Modified:27 Nov 2013 20:40
Publisher:American Association for the Advancement of Science (AAAS)
ISSN:0036-8075
Publisher DOI:10.1126/science.1157956
PubMed ID:18436743
Citations:Web of Science®. Times Cited: 232
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