Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive 

Hermann, M; Ruschitzka, F (2009). The hypertension peril: lessons from CETP inhibitors. Current Hypertension Reports, 11(1):76-80.

Full text not available from this repository.


Pharmacologic inhibitors of the cholesteryl ester transfer protein (CETP) are capable of increasing HDL cholesterol by 50% to 100% in humans. Despite intriguing antiatherogenic effects of CETP inhibition in animal models of atherosclerosis, the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events trial investigators observed an excess of cardiovascular and noncardiovascular morbidity and mortality associated with the use of the CETP inhibitor torcetrapib. This review summarizes available clinical and experimental data about potential underlying mechanisms.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
DDC:610 Medicine & health
Date:February 2009
Deposited On:06 Apr 2009 13:03
Last Modified:28 Nov 2013 00:39
Publisher DOI:10.1007/s11906-009-0014-9
PubMed ID:19146805
Citations:Web of Science®. Times Cited: 3
Google Scholar™
Scopus®. Citation Count: 4

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page