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Epoxide hydrolases: structure, function, mechanism, and assay


Arand, Michael; Cronin, Annette; Adamska, Magdalena; Oesch, Franz (2005). Epoxide hydrolases: structure, function, mechanism, and assay. In: Elsevier. Methods in Enzymology: Phase II Conjugation Enzymes and Transport Systems. New York: Elsevier, 569-588.

Abstract

Epoxide hydrolases are a class of enzymes important in the detoxification of genotoxic compounds, as well as in the control of physiological signaling molecules. This chapter gives an overview on the function, structure, and enzymatic mechanism of structurally characterized epoxide hydrolases and describes selected assays for the quantification of epoxide hydrolase activity.

Abstract

Epoxide hydrolases are a class of enzymes important in the detoxification of genotoxic compounds, as well as in the control of physiological signaling molecules. This chapter gives an overview on the function, structure, and enzymatic mechanism of structurally characterized epoxide hydrolases and describes selected assays for the quantification of epoxide hydrolase activity.

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Additional indexing

Item Type:Book Section, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Pharmacology and Toxicology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2005
Deposited On:22 Oct 2015 14:29
Last Modified:05 Apr 2016 19:27
Publisher:Elsevier
ISSN:0076-6879
Publisher DOI:https://doi.org/10.1016/S0076-6879(05)00032-7
PubMed ID:16399371

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