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Low-intensity late gadolinium enhancement predominates in hypertrophic cardiomyopathy


Naeger, David M; Higgins, Charles; De Marco, Teresa; Muzzarelli, Stefano; Ordovas, Karen G (2015). Low-intensity late gadolinium enhancement predominates in hypertrophic cardiomyopathy. Clinical Imaging, 39(3):432-436.

Abstract

AIM: Assess the extent of low- versus high-intensity late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM).
METHODS: Low- versus high-intensity LGE indexed volumes in 19 HCM patients were compared to 23 myocardial infarction (MI) patients.
RESULTS: Total, low-, and high-intensity LGE volumes in HCM vs. MI were 7.6ml/m(2), 4.7, and 2.4 vs. 11.2, 2.5, and 7.1, respectively. Total LGE volume did not differ (P=.13), though low- and high-intensity did (P=.05, .004). 67% versus 26% of all LGE was low-intensity in HCM versus MI (P<.001).
CONCLUSIONS: LGE in HCM is predominantly low-intensity, so a low threshold may be the most appropriate.

Abstract

AIM: Assess the extent of low- versus high-intensity late gadolinium enhancement (LGE) in hypertrophic cardiomyopathy (HCM).
METHODS: Low- versus high-intensity LGE indexed volumes in 19 HCM patients were compared to 23 myocardial infarction (MI) patients.
RESULTS: Total, low-, and high-intensity LGE volumes in HCM vs. MI were 7.6ml/m(2), 4.7, and 2.4 vs. 11.2, 2.5, and 7.1, respectively. Total LGE volume did not differ (P=.13), though low- and high-intensity did (P=.05, .004). 67% versus 26% of all LGE was low-intensity in HCM versus MI (P<.001).
CONCLUSIONS: LGE in HCM is predominantly low-intensity, so a low threshold may be the most appropriate.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Cardiocentro Ticino
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:14 January 2015
Deposited On:30 Dec 2015 08:36
Last Modified:05 Apr 2016 19:48
Publisher:Elsevier
ISSN:0899-7071
Publisher DOI:https://doi.org/10.1016/j.clinimag.2015.01.001
PubMed ID:25724224

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