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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-11971

Schuepbach, W M M; Emese, B; Loretan, P; Mallet, A; Duru, F; Sanz, E; Meier, B (2008). Non-invasive diagnosis of coronary artery disease using cardiogoniometry performed at rest. Swiss Medical Weekly, 138(15-16):230-238.



PRINCIPLES: Cardiogoniometry is a non-invasive technique for quantitative three-dimensional vectorial analysis of myocardial depolarization and repolarization. We describe a method of surface electrophysiological cardiac assessment using cardiogoniometry performed at rest to detect variables helpful in identifying coronary artery disease. METHODS: Cardiogoniometry was performed in 793 patients prior to diagnostic coronary angiography. Using 13 variables in men and 10 in women, values from 461 patients were retrospectively analyzed to obtain a diagnostic score that would identify patients having coronary artery disease. This score was then prospectively validated on 332 patients. RESULTS: Cardiogoniometry showed a prospective diagnostic sensitivity of 64%, and a specificity of 82%. ECG diagnostic sensitivity was significantly lower, with 53% and a similar specificity of 75%. CONCLUSIONS: Cardiogoniometry is a new, noninvasive, quantitative electrodiagnostic technique which is helpful in identifying patients with coronary artery disease. It can easily be performed at rest and delivers an accurate, automated diagnostic score.



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Contributors:Dep. of cardiology, University Hospital, Inselspital, CH-3010 Bern, Switzerland, Department of cardiology, University hospital of Zurich and Center for Integrative Human Physiology, Zurich, Switzerland, Medical Clinic, Hospital Bern, Tiefenau, Tiefenaustrasse, CH-3004 Bern, Switzerland, Dep. of Biostatistics and Medical Information, Pitié-Salpetriere Medical University, Paris, France
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
DDC:610 Medicine & health
Date:19 April 2008
Deposited On:28 Jan 2009 15:54
Last Modified:28 Nov 2013 00:40
Publisher:EMH Swiss Medical Publishers
Additional Information:Free full text article
Official URL:http://www.smw.ch/docs/pdf200x/2008/15/smw-12040.pdf
Related URLs:http://www.smw.ch/dfe/set_archiv.asp?target=2008/15/smw-12040 (Publisher)
http://www.smw.ch/dfe/set_archiv.asp (Publisher)
PubMed ID:18431698

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