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Systemic and intra-articular anti-inflammatory therapy of temporomandibular joint arthritis in children with juvenile idiopathic arthritis


Stoll, M L; Cron, R Q; Saurenmann, R K (2015). Systemic and intra-articular anti-inflammatory therapy of temporomandibular joint arthritis in children with juvenile idiopathic arthritis. Seminars in Orthodontics, 21(2):125-133.

Abstract

Juvenile idiopathic arthritis (JIA) is a leading cause of acquired disability and malformation in childhood. Although virtually any joint can be affected, one of the most commonly involved yet least frequently recognized joints is the temporomandibular joint (TMJ).1 Persistent arthritis can result in pain, growth problems, cosmetic defects, and poor function, underscoring the necessity of obtaining early control of TMJ arthritis. While the therapy of JIA as a whole has benefitted enormously from the introduction of novel therapeutic agents,2 it remains uncertain to what extent these therapies benefit the TMJ specifically. Thus, many practitioners use intra-articular therapy for refractory TMJ arthritis, although concerns about their long-term safety have been raised.3 Herein, we will review the data on systemic and local anti-inflammatory therapy of TMJ arthritis.

Abstract

Juvenile idiopathic arthritis (JIA) is a leading cause of acquired disability and malformation in childhood. Although virtually any joint can be affected, one of the most commonly involved yet least frequently recognized joints is the temporomandibular joint (TMJ).1 Persistent arthritis can result in pain, growth problems, cosmetic defects, and poor function, underscoring the necessity of obtaining early control of TMJ arthritis. While the therapy of JIA as a whole has benefitted enormously from the introduction of novel therapeutic agents,2 it remains uncertain to what extent these therapies benefit the TMJ specifically. Thus, many practitioners use intra-articular therapy for refractory TMJ arthritis, although concerns about their long-term safety have been raised.3 Herein, we will review the data on systemic and local anti-inflammatory therapy of TMJ arthritis.

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Additional indexing

Item Type:Journal Article, not refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2015
Deposited On:29 Jan 2016 11:28
Last Modified:05 Apr 2016 20:04
Publisher:Elsevier
ISSN:1073-8746
Publisher DOI:https://doi.org/10.1053/j.sodo.2015.02.009

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