Haag, A; Knake, S; Hamer, H M; Boesebeck, F; Freitag, H; Schulz, R; Baum, P; Helmstaedter, C; Wellmer, J; Urbach, H; Hopp, P; Mayer, T; Hufnagel, A; Jokeit, H; Lerche, H; Uttner, I; Meencke, H J; Meierkord, H; Pauli, E; Runge, U; Saar, J; Trinka, E; Benke, T; Vulliemoz, S; Wiegand, G; Stephani, U; Wieser, H G; Rating, D; Werhahn, K; Noachtar, S; Schulze-Bonhage, A; Wagner, K; Alpherts, W C J; van Emde Boas, W; Rosenow, F (2008). The Wada test in Austrian, Dutch, German, and Swiss epilepsy centers from 2000 to 2005: a review of 1421 procedures. Epilepsy & Behavior : E&B, 13(1):83-89.
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Twenty-six Austrian, Dutch, German, and Swiss epilepsy centers were asked to report on use of the Wada test (intracarotid amobarbital procedure, IAP) from 2000 to 2005 and to give their opinion regarding its role in the presurgical diagnosis of epilepsy. Sixteen of the 23 centers providing information had performed 1421 Wada tests, predominantly the classic bilateral procedure (73%). A slight nonsignificant decrease over time in Wada test frequency, despite slightly increasing numbers of resective procedures, could be observed. Complication rates were relatively low (1.09%; 0.36% with permanent deficit). Test protocols were similar even though no universal standard protocol exists. Clinicians rated the Wada test as having good reliability and validity for language determination, whereas they questioned its reliability and validity for memory lateralization. Several noninvasive functional imaging techniques are already in use. However, clinicians currently do not want to rely solely on noninvasive functional imaging in all patients.
|Contributors:||Arbeitsgemeinschaft für Prächirurgische Epilepsiediagnostik und Operative Epilepsietherapie e.V.|
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology|
|DDC:||610 Medicine & health|
|Deposited On:||02 Feb 2009 14:53|
|Last Modified:||28 Nov 2013 00:53|
|Citations:||Web of Science®. Times cited: 21|
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