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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-12373

Cioffi, I; Martina, R; Michelotti, A; Chiodini, P; Tagliaferri, R; Farella, M (2008). Web-based randomised controlled trials in orthodontics. Evidence-Based Dentistry, 9(4):118-120.

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Randomised controlled trials (RCT) are considered the best source of scientific evidence--the gold standard--when evaluating the efficacy of orthodontic treatments. Frequently, RCT are planned as multicentre trials, with the intention of increasing statistical power and raising the precision of outcome estimates. The management of large-scale RCT, however, requires even more thorough organisation than conventional RCT. Indeed, the need for high accuracy and standardisation in data collection, research aids, secretarial skills, staff and patient training, and organisational meetings, make these studies time-consuming, expensive and, in general, relatively complex to carry out well. A website was developed to support a large scale-orthodontic RCT which aimed to evaluate the efficacy of a functional appliance(www.ortodonzia.unina.it). Websites such as this can increase the quality of data collection, simplify the randomisation process, speed up data collection, and improve trial monitoring. Web-based RCT have the potential to help globalise orthodontic research and also increase our rate of acquisition of evidence in orthodontics.




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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Clinic for Masticatory Disorders and Complete Dentures, Geriatric and Special Care Dentistry
Dewey Decimal Classification:610 Medicine & health
Deposited On:05 Feb 2009 17:05
Last Modified:05 Apr 2016 12:56
Publisher:Nature Publishing Group
Publisher DOI:10.1038/sj.ebd.6400618
PubMed ID:19151687

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