Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-12446
Wiegering, V A; Kellenberger, C J; Bodmer, N; Bergstraesser, E; Niggli, F K; Grotzer, M A; Nadal, D; Bourquin, J P (2008). Conservative management of acute appendicitis in children with hematologic malignancies during chemotherapy-induced neutropenia. Journal of Pediatric Hematology/Oncology, 30(6):464-467.
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The management of acute appendicitis in the febrile neutropenic patient after intensive chemotherapy is controversial. We report our single-center-experience of 5 children diagnosed with appendicitis during febrile neutropenia after chemotherapy for acute leukemia or lymphoma. All patients presented with an isolated appendicitis without signs of overt mucositis or more diffuse enterocolitis. The clinical diagnosis was confirmed by ultrasonography. Perforation with retrocecal abscess was present in 1 patient. Administration of combination antimicrobial regimens including meropenem resulted in complete resolution in all patients. Our observations indicate that acute appendicitis in clinically stable neutropenic cancer patients can be managed conservatively without surgery.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic|
|DDC:||610 Medicine & health|
|Deposited On:||05 Feb 2009 09:43|
|Last Modified:||02 Dec 2013 21:55|
|Publisher:||Lippincott Wiliams & Wilkins|
|Citations:||Web of Science®. Times cited: 9|
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