Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Zuzak, T J; Poretti, A; Drexel, B; Zehnder, D; Boltshauser, E; Grotzer, M A (2008). Outcome of children with low-grade cerebellar astrocytoma: long-term complications and quality of life. Child's Nervous System, 24(12):1447-1455.

Full text not available from this repository.

Abstract

OBJECTS: To study the long-term outcome of surgically treated low-grade cerebellar astrocytomas in children. MATERIALS AND METHODS: We followed 31 consecutive patients under 16 years of age who were diagnosed between 1980 and 2005 in a single institution. In 21 of 31 survivors (median follow-up time 7.9 years; range 5.6-27.4 years) who agreed to participate, tumor control, neurological and cognitive complications, and their impact on behavioral and emotional adjustment and health-related quality of life (HRQoL) were comprehensively assessed qualitatively and quantitatively. RESULTS: Neurological sequelae were found in 43%. However, age-appropriate ability to perform daily life activities was normal in all patients. Remarkably, cognitive deficits leading to significant school problems occurred in 19% and behavioral and emotional adjustment disturbances in 27%. In comparison with healthy controls, the survivors rated their HRQoL similarly or even higher. CONCLUSION: Childhood low-grade cerebellar astrocytomas have an excellent cure rate by tumor surgery alone. When compared with other pediatric brain tumors, the risk of neurological, cognitive, emotional, and behavioral complications is relatively small. HRQoL is similar to that of healthy controls.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
DDC:610 Medicine & health
Language:English
Date:2008
Deposited On:05 Feb 2009 09:09
Last Modified:27 Nov 2013 20:42
Publisher:Springer
ISSN:0256-7040
Publisher DOI:10.1007/s00381-008-0692-7
PubMed ID:18690461
Citations:Web of Science®. Times Cited: 10
Google Scholar™

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page