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Wenger, R H (2004). Sauerstoffhomöostase in Gewebe und Zelle: Wie Sauerstoffmangel die Genexpression reguliert. Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie, 39(S1):S38-S43.

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Every cell of the body is capable of measuring the environmental oxygen concentration. When oxygen supply falls below oxygen demand of the cell (hypoxia), a series of genes will be activated whose products help the cell, the tissue as well as the whole organism in adapting to these altered oxygen concentrations. The discovery of hypoxia-inducible transcription factors (HIFs) allowed the molecular understanding of these processes.



Additional indexing

Other titles:[Oxygen homeostasis in tissues and cells: how hypoxia regulates gene expression.]
Item Type:Journal Article, refereed
Communities & Collections:04 Faculty of Medicine > Institute of Physiology
07 Faculty of Science > Institute of Physiology
Dewey Decimal Classification:570 Life sciences; biology
Deposited On:11 Feb 2008 12:22
Last Modified:05 Apr 2016 12:18
Publisher DOI:10.1055/s-2004-818822
PubMed ID:15490340

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