Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-14309
Rühli, Frank J; Henneberg, Maciej; Schär, Dominik J; Imhof, Alexander; Schleiffenbaum, Boris; Woitek, Ulrich (2008). Determinants of inter-individual cholesterol levels variations in an unbiased young male sample. Swiss Medical Weekly, 138(19-20):286-291.
Question under study: Affected by individual life style, total cholesterol serum level is a major morbidity and mortality risk factor for atherosclerotic cardiovascular disease (CVD). We present total cholesterol values and possible etiological factors of young Swiss conscripts. Particularly, we focus on the varying impact of such a component depending on different levels of individual cholesterol.
Methods: Male conscripts (n=19’272) of the 2005 census of the conscripts have been examined, reflecting ca. 59% of a total Swiss male citizen birth cohort. Quantile regression allows us to analyze the reagibility of arbitrary quantiles with respect to variables of interest.
Results: Eleven percent of all conscripts show an increased total cholesterol level. A major association of high individual cholesterol level is with French mother tongue. The largest socio-economic subsample – agricultural and construction sectors – show significantly higher individual cholesterol levels than employees in the industry sector and students, respectively.
Conclusions: We were able to find and exclude various as yet unstudied factors influencing individual total cholesterol levels. Such a screening programme offers a unique opportunity to target persons at high-risk for CVD morbidity and mortality already early in life.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||03 Faculty of Economics > Department of Economics
04 Faculty of Medicine > University Hospital Zurich > Clinic and Policlinic for Internal Medicine
06 Faculty of Arts > Institute of History
04 Faculty of Medicine > Institute of Evolutionary Medicine
04 Faculty of Medicine > Institute of Anatomy
|DDC:||570 Life sciences; biology
610 Medicine & health
|Deposited On:||20 Feb 2009 10:29|
|Last Modified:||25 Sep 2014 11:32|
|Publisher:||EMH Swiss Medical Publishers|
|Additional Information:||Free full text article|
|Related URLs:||http://www.smw.ch/dfe/set_archiv.asp (Publisher)|
|Citations:||Web of Science®. Times Cited: 8|
Scopus®. Citation Count: 10
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