Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-14449
Maurer, U; Brem, S; Bucher, K; Kranz, F; Benz, R; Steinhausen, H C; Brandeis, D (2007). Impaired tuning of a fast occipito-temporal response for print in dyslexic children learning to read. Brain: A Journal of Neurology, 130(12):3200-3210.
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Developmental dyslexia is defined as a disorder of learning to read. It is thus critical to examine the neural processes that impair learning to read during the early phase of reading acquisition, before compensatory mechanisms are adapted by older readers with dyslexia. Using electroencephalography-based event-related imaging, we investigated how tuning of visual activity for print advances in the same children before and after initial reading training in school. The focus was on a fast, coarse form of visual tuning for print, measured as an increase of the occipito-temporal N1 response at 150-270 ms in the event-related potential (ERP) to words compared to symbol strings. The results demonstrate that the initial development of reading skills and visual tuning for print progressed more slowly in those children who became dyslexic than in their control peers. Print-specific tuning in 2nd grade strongly distinguished dyslexic children from controls. It was maximal in the inferior occipito-temporal cortex, left-lateralized in controls, and reduced in dyslexic children. The results suggest that delayed initial visual tuning for print critically contributes to the development of dyslexia.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Center for Child and Adolescent Psychiatry|
04 Faculty of Medicine > Center for Integrative Human Physiology
|DDC:||570 Life sciences; biology|
610 Medicine & health
|Deposited On:||19 Mar 2009 17:52|
|Last Modified:||28 Nov 2013 02:57|
|Publisher:||Oxford University Press|
|Citations:||Web of Science®. Times cited: 54|
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