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A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans


de Quervain, D J F; Kolassa, I T; Ertl, V; Onyut, P L; Neuner, F; Elbert, T; Papassotiropoulos, A (2007). A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans. Nature Neuroscience, 10(9):1137-1139.

Abstract

Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the alpha2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in survivors of the Rwandan civil war who experienced highly aversive emotional situations.

Emotionally arousing events are recalled better than neutral events. This phenomenon, which helps us to remember important and potentially vital information, depends on the activation of noradrenergic transmission in the brain. Here we show that a deletion variant of ADRA2B, the gene encoding the alpha2b-adrenergic receptor, is related to enhanced emotional memory in healthy Swiss subjects and in survivors of the Rwandan civil war who experienced highly aversive emotional situations.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Division of Psychiatric Research and Clinic for Psychogeriatric Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Psychiatry and Psychotherapy
04 Faculty of Medicine > Center for Integrative Human Physiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:September 2007
Deposited On:18 Mar 2009 09:02
Last Modified:05 Apr 2016 13:03
Publisher:Nature Publishing Group
ISSN:1097-6256
Publisher DOI:10.1038/nn1945
PubMed ID:17660814
Permanent URL: http://doi.org/10.5167/uzh-14455

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