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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-15719

Guibert, G; Munnik, F; Langhoff, J D; von Rechenberg, Brigitte; Buffat, A; Laub, D; Faber, L (2008). Study of new sheep bone and Zn/Ca ratio around TiAlV screw: PIXE–RBS analysis. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 266(5):813-819.

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This study reports on in vivo particle induced X-ray emission (PIXE) measurements combined with Rutherford backscattering spectroscopy (RBS) analyses of new remodeled sheep bone formed around TiAIV screws. The implants (screws) were anodized by a modified TiMax (TM) process. The interface between the implant and the bone was carefully investigated. [Zn]/[Ca] in-depth composition profiles as well as Ca, Fe elemental maps were recorded. The thickness of new bone formed around the screw reached 300 - 400 mu m. Osteon and Osteoid phases were identified in the new bone. A higher [Zn]/[Ca] ratio was observed in the new bone as compared to the mature bone. Blood vessels were observed in the bone in close contact with the screw. This study shows the potential of ion beam analysis for biological and biomedical characterization.


4 citations in Web of Science®
6 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Equine Department
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Uncontrolled Keywords:PIXE–RBS method; Biomaterials; New bone; Zn
Date:March 2008
Deposited On:20 Feb 2009 15:10
Last Modified:04 Jun 2016 07:24
Publisher DOI:10.1016/j.nimb.2008.01.025

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