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Immune regulation by histamine H4 receptors in skin


Akdis, C A (2008). Immune regulation by histamine H4 receptors in skin. Journal of Investigative Dermatology, 128(7):1615-1616.

Abstract

The diverse effects of histamine on immune regulation appear to be due to differential expression and regulation of four types of histamine receptors and their distinct intracellular signals. The differences in cellular expression and affinities of these receptors for histamine determine the biological effects of histamine and the drugs that target histamine receptors. In this issue, Dijkstra et al., demonstrate the expression and some of the functions of histamine H(4) receptors on inflammatory dendritic cells in atopic dermatitis skin.

The diverse effects of histamine on immune regulation appear to be due to differential expression and regulation of four types of histamine receptors and their distinct intracellular signals. The differences in cellular expression and affinities of these receptors for histamine determine the biological effects of histamine and the drugs that target histamine receptors. In this issue, Dijkstra et al., demonstrate the expression and some of the functions of histamine H(4) receptors on inflammatory dendritic cells in atopic dermatitis skin.

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5 citations in Web of Science®
5 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Swiss Institute of Allergy and Asthma Research
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2008
Deposited On:22 Feb 2009 09:44
Last Modified:05 Apr 2016 13:04
Publisher:Nature Publishing Group
ISSN:0022-202X
Publisher DOI:https://doi.org/10.1038/jid.2008.144
PubMed ID:18548077
Permanent URL: https://doi.org/10.5167/uzh-15832

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