Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-16115

Rios, D; Magalhães, A C; Polo, R O B; Wiegand, A; Attin, T; Buzalaf, M A R (2008). The efficacy of a highly concentrated fluoride dentifrice on bovine enamel subjected to erosion and abrasion. Journal of the American Dental Association, 139(12):1652-1656.

[img]Accepted Version
PDF - Repository staff only


BACKGROUND: Researchers have proposed the use of fluoride for the prevention of enamel wear; however, only limited information is available about the impact of fluoridated dentifrices. Because tooth wear is a well-recognized dental problem, the authors conducted an in situ, ex vivo study to assess the efficacy of a highly concentrated fluoride dentifrice on bovine enamel subjected to erosion and abrasion. METHODS: The authors conducted a double-blind, crossover in situ study consisting of three phases (seven days each). In each phase, the authors tested one of the dentifrices (5,000 parts per million fluoride [F]; 1,100 ppm F; no F). They performed erosive challenges with the use of cola drink (60 seconds, four times per day) and abrasive challenges via toothbrushing (30 seconds, four times per day). The authors determined the enamel loss via profilometry. RESULTS: The authors tested the data by using two-way analysis of variance (P < .05). For the erosion-plus-abrasion condition, the study results showed that enamel wear was significantly higher than that with erosion alone. The findings showed no significant differences between the dentifrices regarding enamel wear. CONCLUSIONS: Within the in situ, ex vivo conditions of this study, the authors concluded that the highly concentrated fluoride dentifrice did not have a protective effect on enamel against erosion and erosion plus toothbrushing abrasion. CLINICAL IMPLICATIONS: Patients at risk of developing enamel erosion should benefit from preventive measures other than fluoride dentifrice, because even a highly concentrated fluoride dentifrice does not appear to prevent enamel erosion.


27 citations in Web of Science®
36 citations in Scopus®
Google Scholar™


1 download since deposited on 27 Feb 2009
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Clinic for Preventive Dentistry, Periodontology and Cariology
Dewey Decimal Classification:610 Medicine & health
Date:December 2008
Deposited On:27 Feb 2009 11:37
Last Modified:05 Apr 2016 13:05
Publisher:American Dental Association
Official URL:http://jada.ada.org/cgi/reprint/139/12/1652
Related URLs:http://jada.ada.org/ (Publisher)
PubMed ID:19047671

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page