Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-16531
Kuschel, S; Werner, M; Schmid, D M; Faust, E; Schuessler, B (2008). Botulinum toxin-A for idiopathic overactivity of the vesical detrusor: a 2-year follow-up. International Urogynecology Journal, 19(7):905-909.
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The aim of this trial was to examine the effects after 2 years of a single intravesical botulinum toxin-A injection (BTX-A). This prospective, observational study was conducted using urodynamic measurements and quality of life (QoL) assessment to document the effect after 2 years of a single 100 I.U. injection of BTX-A into the vesical detrusor muscle. Twenty-six patients were followed up for 2 years after a first intravesical BTX-A injection. Of these 26 patients, one was a primary failure, three were lost to follow-up, and 11 patients had a repeated injection at 5-26 months (one patient had a third injection). Seven of the remaining 11 patients in the single injection group were recommended repeated injection or another treatment, and four required no other treatment. In conclusion, 2 years after a single BTX-A injection statistically significant differences in urodynamics and an improvement in QoL could still be demonstrated.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Urological Clinic|
|DDC:||610 Medicine & health|
|Deposited On:||25 Feb 2009 10:52|
|Last Modified:||27 Nov 2013 23:10|
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