Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-16607
Kunin, V; Raes, J; Harris, J K; Spear, J R; Walker, J J; Ivanova, N; von Mering, C; Bebout, B M; Pace, N R; Bork, P; Hugenholtz, P (2008). Millimeter-scale genetic gradients and community-level molecular convergence in a hypersaline microbial mat. Molecular Systems Biology, 4:198.
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To investigate the extent of genetic stratification in structured microbial communities, we compared the metagenomes of 10 successive layers of a phylogenetically complex hypersaline mat from Guerrero Negro, Mexico. We found pronounced millimeter-scale genetic gradients that were consistent with the physicochemical profile of the mat. Despite these gradients, all layers displayed near-identical and acid-shifted isoelectric point profiles due to a molecular convergence of amino-acid usage, indicating that hypersalinity enforces an overriding selective pressure on the mat community.
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|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||07 Faculty of Science > Institute of Molecular Life Sciences
08 University Research Priority Programs > Systems Biology / Functional Genomics
|DDC:||570 Life sciences; biology|
|Deposited On:||08 Mar 2009 19:08|
|Last Modified:||23 Nov 2012 13:03|
|Publisher:||Nature Publishing Group|
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