Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-16724
Münz, C (2008). Non-cytotoxic protection by human NK cells in mucosal secondary lymphoid tissues. European Journal of Immunology, 38(11):2946-2948.
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Even though NK cells have been named for their spontaneous cytotoxicity, a large subpopulation of human NK cells primarily responds to activation with cytokine secretion and not killing. These CD56brightCD16(-) NK cells are abundant in secondary lymphoid tissues, can restrict pathogens that have breached mucosal barriers, and assist Th1 polarization during immune response priming. This exciting new aspect of NK-cell biology is discussed in this viewpoint.
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Institute of Experimental Immunology|
|DDC:||570 Life sciences; biology|
610 Medicine & health
|Deposited On:||11 Jan 2010 14:13|
|Last Modified:||27 Nov 2013 21:00|
|Additional Information:||The definitive version is available at www.blackwell-synergy.com|
|Citations:||Web of Science®. Times cited: 10|
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