Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-18004
Kaiser, Claire I; Fidel, Janean L; Roos, Malgorzata; Kaser-Hotz, Barbara (2007). Reevaluation of the University of Wisconsin 2-year protocol for treating canine lymphosarcoma. Journal of the American Animal Hospital Association, 43(2):85-92.
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This retrospective study investigated a population of 96 dogs with newly diagnosed malignant lymphosarcoma that were treated with the commonly used University of Wisconsin-Madison (UW-M) chemotherapy protocol. Pretreatment characteristics were analyzed to determine prognostic factors. Dogs with higher World Health Organization (WHO) stages (including stage IV) and dogs with hypercalcemia were at significantly higher risk of relapse (P=0.018 and P=0.016, respectively). Dose reduction, treatment delays, and prior therapy with cortico-steroids were not associated with clinical outcome. First remission duration of 270 days was similar to historically reported data. Overall survival time of 218 days was much shorter than historical data.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Institute of Social and Preventive Medicine|
|DDC:||610 Medicine & health|
|Deposited On:||27 Mar 2009 16:49|
|Last Modified:||01 Dec 2013 02:19|
|Publisher:||AAHA: American Animal Hospital Assioation|
|Citations:||Web of Science®. Times cited: 5|
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