Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Maintenance: Tuesday, July the 26th 2016, 07:00-10:00

ZORA's new graphical user interface will be relaunched (For further infos watch out slideshow ZORA: Neues Look & Feel). There will be short interrupts on ZORA Service between 07:00am and 10:00 am. Please be patient.

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-18704

Deplazes, P; Jimenez-Palacios, S; Gottstein, B; Skaggs, J; Eckert, J (1994). Detection of Echinococcus coproantigens in stray dogs of northern Spain. Applied Parasitology, 35(4):297-301.

[img] PDF - Registered users only


An enzyme-linked immunosorbent assay (ELISA) was assessed for its suitability to diagnostically detect Echinococcus coproantigens in fecal samples of dogs infected with E. granulosus. The specificity of the test was determined by investigating fecal samples from 177 Echinococcus-free dogs infected with Taenia spp., 41 dogs with non-taeniid helminths and 24 dogs free of helminth infections. An overall specificity of 97% was determined. The diagnostic sensitivity was in close association to the worm burden of infected individuals: when dogs harboured less than 100 worms, six from 21 samples (29%) were found to be positive in coproantigen ELISA, whereas sensitivity was much higher (23 ELISA-positive from 25 samples = 92%) when dogs had more than 100 worms. Despite the relatively low average sensitivity (63%), the test enabled detection of more than 90% of the biomass of adult Echinococcus present in the respective dog populations. Conclusively, coproantigen detection allows diagnosis of most individual intestinal Echinococcus infections relevant for the egg contamination of the environment and is therefore a valuable tool to determine the relative prevalence of adult stage E. granulosus prevalence in a given endemic area.



1 download since deposited on 03 Jun 2009
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Parasitology
04 Faculty of Medicine > Institute of Parasitology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
600 Technology
Deposited On:03 Jun 2009 07:21
Last Modified:05 Apr 2016 13:14
Publisher:Urban und Fischer Verlag
PubMed ID:7812318

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page