Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Russmann, H; Vingerhoets, F; Miklossy, J; Maeder, P; Glatzel, M; Aguzzi, A; Bogousslavsky, J (2005). Sporadic Creutzfeldt-Jakob disease: a comparison of pathological findings and diffusion weighted imaging. Journal of Neurology, 252(3):338-342.

Full text not available from this repository.

Abstract

To investigate a possible relationship between the severity of pathological and radiological lesions in diffusion-weighted MRI (DWI) we compared DWI findings from 6 sequential brain MRI scans with pathological features of numerous tissue blocks of different cortical and subcortical regions in a case of autopsy-proven sporadic CJD. Whereas DWI and pathological examination revealed multifocal, cortical and deep hyperintensities at corresponding localizations, no correlation between the degree of severity of radiologically visible and pathological damage was found.The characteristic focal involvement and extension of lesions of the cortex and the basal ganglia bilaterally shown by DWI may be an argument for the spreading of the disease per contiguitatem.

Item Type:Journal Article, refereed
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Neuropathology
DDC:570 Life sciences; biology
610 Medicine & health
Language:English
Date:01 March 2005
Deposited On:11 Feb 2008 13:26
Last Modified:27 Nov 2013 22:41
Publisher:Springer
ISSN:0340-5354
Publisher DOI:10.1007/s00415-005-0648-8
PubMed ID:15739045
Citations:Web of Science®. Times Cited: 16
Google Scholar™

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page