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An ultrasound assisted anchoring technique (BoneWelding Technology) for fixation of implants to bone: A histological pilot study in sheep


Langhoff, Jens D; Kümmerle, Jan M; Mayer, Joerg; Weber, Urs; Berra, Milica; Mueller, Jessika M; Kästner, Sabine Beate Rita; Zlinszky, Katalin; Auer, Jörg A; von Rechenberg, Brigitte (2009). An ultrasound assisted anchoring technique (BoneWelding Technology) for fixation of implants to bone: A histological pilot study in sheep. The Open Orthopaedics Journal, 3:40-47.

Abstract

The BoneWelding® Technology offers new opportunities to anchor implants within bone. The technology
melted the surface of biodegradable polymer pins by means of ultrasound energy to mould material into the structures of the predrilled bone. Temperature changes were measured at the sites of implantation in an in vitro experiment. In the in vivo part of the study two types of implants were implanted in the limb of sheep to investigate the biocompatibility of the method. One implant type was made of PL-DL-lactide (PLA), the second one was a titanium core partially covered with PLA. Healing period was 2 and 6 months, with 3 sheep per group. Bone samples were evaluated radiologically, histologically and histomorphometrically for bone remodeling and inflammatory reactions. Results demonstrated mild and short temperature increase during insertion. New bone formed at the implant without evidence of inflammatory reaction.
The amount of adjacent bone was increased compared to normal cancellous bone. It was concluded that the
BoneWelding® Technology proved to be a biocompatible technology to anchor biodegradable as well as titanium-PLA
implants in bone.

The BoneWelding® Technology offers new opportunities to anchor implants within bone. The technology
melted the surface of biodegradable polymer pins by means of ultrasound energy to mould material into the structures of the predrilled bone. Temperature changes were measured at the sites of implantation in an in vitro experiment. In the in vivo part of the study two types of implants were implanted in the limb of sheep to investigate the biocompatibility of the method. One implant type was made of PL-DL-lactide (PLA), the second one was a titanium core partially covered with PLA. Healing period was 2 and 6 months, with 3 sheep per group. Bone samples were evaluated radiologically, histologically and histomorphometrically for bone remodeling and inflammatory reactions. Results demonstrated mild and short temperature increase during insertion. New bone formed at the implant without evidence of inflammatory reaction.
The amount of adjacent bone was increased compared to normal cancellous bone. It was concluded that the
BoneWelding® Technology proved to be a biocompatible technology to anchor biodegradable as well as titanium-PLA
implants in bone.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Equine Department
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:2009
Deposited On:03 Jun 2009 14:03
Last Modified:10 May 2016 15:49
Publisher:Bentham Open
ISSN:1874-3250
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:10.2174/1874325000903010040
PubMed ID:19572033
Permanent URL: http://doi.org/10.5167/uzh-18760

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