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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-18944

Mueller, Fabienne; Poirier, Valerie; Melzer, Katja; Nitzl, Dagmar; Roos, Malgorzata; Kaser-Hotz, Barbara (2005). Palliative radiotherapy with electrons of appendicular osteosarcoma in 54 dogs. In vivo (Athens, Greece), 19(4):713-716.

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Abstract

Radiotherapy is effective for the palliation of pain associated with primary and metastatic bony neoplasia in dogs and humans, but no standard treatment protocol has been established. The goal of this study was to evaluate a 3 x 8 Gy and a 4 x 6 Gy protocol using electrons with a betatron or linear accelerator for the treatment of appendicular osteosarcoma in 54 dogs. Thirty-three dogs received chemotherapy consisting of carboplatin IV concurrently with radiotherapy. Eighty-three % (n = 45) of the dogs experienced pain relief during or following treatment. The median duration of pain relief from treatment start was 53 days. In conclusion, both protocols are effective for palliation of clinical signs of canine appendicular osteosarcoma. The outcome reported here is similar to the results of other studies using Co photons. The use of chemotherapy did not improve the response to radiotherapy.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Social and Preventive Medicine
DDC:610 Medicine & health
Language:English
Date:2005
Deposited On:10 Jun 2009 14:03
Last Modified:14 Jan 2013 16:16
Publisher:Dr. J.G. Delinassios
ISSN:0258-851X
PubMed ID:15999538
Citations:Google Scholarā„¢

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