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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-19331

Reiner, C S; Karlo, C; Petrowsky, H; Marincek, B; Weishaupt, D; Frauenfelder, T (2009). Preoperative liver volumetry: how does the slice thickness influence the multidetector computed tomography- and magnetic resonance-liver volume measurements? Journal of Computer Assisted Tomography, 33(3):390-397.

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OBJECTIVE: The purpose was to investigate the influence of slice thickness on multidetector computed tomography (MDCT)- and magnetic resonance (MR)-based liver volumetry. MATERIALS AND METHODS: Twenty patients who underwent liver surgery were imaged with either a 64-slice MDCT (n = 10) or a 1.5-T MR scanner (n = 10). Multidetector computed tomography and MR images were reconstructed using different slice thicknesses (2, 4, 6, and 8 mm). Total liver volumes (TLVs) were measured by 2 independent readers based on different slice thicknesses using semiautomatic software. Results were compared with TLVs based on 2-mm slices that served as standard of reference. The time to perform each volumetry was recorded. RESULTS: For MDCT volumetry, a statistical difference was seen only between TLVs based on 2-mm versus 8-mm slices (P = 0.012 and P = 0.002 for readers 1 and 2, respectively). For MR volumetry, no statistical difference was seen between TLVs of the standard of reference and TLVs based on 4-, 6-, and 8-mm slices. Regarding the time to perform volumetry, there was a significant gain of time for both readers when volumetry was performed on 6- and 8-mm MDCT slices and on 4-, 6-, and 8-mm MR slices (P < 0.0167) when compared with the standard of reference. CONCLUSIONS: The results of MDCT- and MR-based liver volumetry are dependent on slice thickness. With respect to the precision of calculated volumes and the significant gain of time, 6-mm slices are preferable for computed tomographic imaging, and 8-mm slices are preferable for MR imaging.


14 citations in Web of Science®
15 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
Dewey Decimal Classification:610 Medicine & health
Deposited On:22 Jun 2009 14:06
Last Modified:05 Apr 2016 13:16
Publisher:Lippincott Wiliams & Wilkins
Publisher DOI:10.1097/RCT.0b013e3181806c29
PubMed ID:19478632

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