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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-19447

Goerres, G W; Michel, S C A; Fehr, M K; Kaim, A H; Steinert, H C; Seifert, B; von Schulthess, G K; Kubik-Huch, R A (2003). Follow-up of women with breast cancer: comparison between MRI and FDG PET. European Radiology, 13(7):1635-1644.

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Abstract

The aim of this study was to compare MRI of the breast with (18)F-fluoro-deoxy-glucose (FDG) positron emission tomography (PET) in patients with suspected local or regional breast cancer recurrence or suspected contralateral breast cancer. Thirty-two patients (mean age 57.2 years, age range 32-76 years) with suspected loco-regional recurrence ( n=19), chest wall recurrence ( n=5), and suspected secondary tumor of the contralateral breast ( n=8) underwent MRI of the breast and FDG PET of the whole body and breast region. Cytology/histology ( n=17) or a clinical follow-up examination ( n=15) with additional imaging served as the standard of reference. A McNemar test was performed to compare PET and MRI, and kappa was determined to quantify agreement of both methods. Sensitivity was 79 and 100%, specificity was 94 and 72%, and accuracy was 88 and 84% for MRI and PET, respectively. Additional metastases outside the field of view of MRI were found in PET in 5 patients. In this study both imaging methods had comparable accuracy. The detection of distant metastases with whole-body PET imaging can influence patient management.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Social and Preventive Medicine
DDC:610 Medicine & health
Date:2003
Deposited On:29 Jun 2009 08:54
Last Modified:27 Nov 2013 20:13
Publisher:Springer
ISSN:0938-7994
Additional Information:The original publication is available at www.springerlink.com
Publisher DOI:10.1007/s00330-002-1720-8
PubMed ID:12835979
Citations:Web of Science®. Times Cited: 62
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