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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-19676

Müller, D W H; Szentiks, C; Wibbelt, G (2009). Polycystic Kidney Disease in Adult Brazilian Agoutis (Dasyprocta leporina). Veterinary Pathology, 46(4):656-661.

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During the last 21 years seven adult captive Brazilian agoutis (Dasyprocta leporina) from four different zoological gardens were necropsied and histologically examined at the Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany. All animals had polycystic kidney disease as the major pathological change. Except in one case, no clinical signs were recognized prior to death. The animals had macroscopic bilateral alterations of the kidneys ranging from granulated surfaces to severe polycystic changes. Microscopic examination revealed multifocal to generalized, moderate to severe cystic dilatations of Bowman’s capsules and renal tubules, moderate mesangial and capsular proliferation of the renal corpuscles, mild interstitial fibrosis and mild to moderate interstitial lympho-plasmacytic infiltrations. Little information is known about the genetic relationships of these animals, but breeding practice indicates a high possibility of inbred agouti zoo populations in Germany. This is the first report on polycystic kidney disease in Brazilian agoutis with presumed genetic background.


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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Date:9 March 2009
Deposited On:10 Jul 2009 14:32
Last Modified:05 Apr 2016 13:17
Publisher:American College of Veterinary Pathologists
Publisher DOI:10.1354/vp.08-VP-0107-W-FL

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