Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Heppner, F L; Arrighi, I; Kalinke, U; Aguzzi, A (2001). Immunity against prions? Trends in Molecular Medicine, 7(11):477-479.

Full text not available from this repository.

View at publisher

Abstract

Several recent reports indicate that antibodies directed against the cellular form of the prion protein, PrPC, might eliminate the transmissible agent of spongiform encephalopathies (the prion) from scrapie-infected cells in vitro, and that a humoral immune response could prevent scrapie pathogenesis in vivo. These findings suggest that immunotherapeutical intervention against prion diseases is not unattainable. Will vaccines and post-exposure strategies based on antibodies ever prove useful against scrapie, bovine spongiform encephalopathy (BSE), or Creutzfeldt–Jakob disease?

Citations

Altmetrics

Downloads

0 downloads since deposited on 11 Feb 2008
0 downloads since 12 months

Additional indexing

Item Type:Journal Article, refereed
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Neuropathology
DDC:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2001
Deposited On:11 Feb 2008 12:27
Last Modified:27 Nov 2013 19:45
Publisher:Elsevier
ISSN:1471-4914
Publisher DOI:10.1016/S1471-4914(01)02182-7
PubMed ID:11689311

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page