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Prion diseases, blood and the immune system: concerns and reality.


Aguzzi, A (2000). Prion diseases, blood and the immune system: concerns and reality. Haematologica / The Hematology Journal, 81(1):3-10.

Abstract

There is a great amount of uncertainty about the nature of the agent which causes spongiform encephalopathies. In recent years the occurrence of bovine spongiform encephalopathy and of new variant-Creutzfeldt Jakob disease, has raised concerns that prions may, under certain circumstances, contaminate the blood supply. This review article illustrates the problems with which research in this field is fraught, and presents some of the arguments which are controversially discussed in the field.

There is a great amount of uncertainty about the nature of the agent which causes spongiform encephalopathies. In recent years the occurrence of bovine spongiform encephalopathy and of new variant-Creutzfeldt Jakob disease, has raised concerns that prions may, under certain circumstances, contaminate the blood supply. This review article illustrates the problems with which research in this field is fraught, and presents some of the arguments which are controversially discussed in the field.

Citations

48 citations in Web of Science®
49 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Neuropathology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2000
Deposited On:11 Feb 2008 12:27
Last Modified:05 Apr 2016 12:21
Publisher:Ferrata Storti Foundation
ISSN:0390-6078
Related URLs:http://www.haematologica.org/journal/2000/85003.pdf
PubMed ID:10627667

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