Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-20265

Husmann, L; Tatsugami, F; Aepli, U; Herzog, B A; Valenta, I; Veit-Haibach, P; Buechel, R R; Pazhenkottil, A P; Gaemperli, O; Burkhard, N; Wyss, C A; Kaufmann, P A (2009). Prevalence of noncardiac findings on low dose 64-slice computed tomography used for attenuation correction in myocardial perfusion imaging with SPECT. International Journal of Cardiovascular Imaging, 25(8):859-865.

[img] PDF - Registered users only
View at publisher


Electrocardiogram (ECG)-triggered, low dose computed tomography (CT) is increasingly used for attenuation correction in myocardial perfusion imaging (MPI) with SPECT. The purpose of the study was to assess the prevalence of relevant noncardiac findings in the field-of-view of such attenuation correction CT scans. Five hundred and eighty-two consecutive patients (211 female, 371 male; mean age: 64 +/- 11 years; BMI: 27.7 +/- 5.3 kg/m(2)) underwent 64-slice, ECG-triggered CT scanning for attenuation correction of MPI with SPECT. Relevant findings were defined as abnormalities that required clinical or radiological follow-up. Noncardiac findings were detected in 400 patients (68.7%). In 196 patients (33.7%) 226 relevant findings were detected. Findings included noncalcified pulmonary nodules (n = 156), interstitial lung disease (n = 6), pleural effusion (n = 20), pneumonia (n = 1), aortic aneurysm (n = 5), aortic dissection (n = 4), enlarged mediastinal lymph nodes (n = 5), mediastinal tumor (n = 3), breast abnormalities (n = 3), liver cirrhosis (n = 5), liver mass (n = 5), ascites (n = 5), splenomegaly (n = 2), renal mass (n = 1), hydronephrosis (n = 1), adrenal mass (n = 3), and bone metastasis (n = 1). As low dose 64-slice CT scans used for attenuation correction in MPI with SPECT reveal a high prevalence of noncardiac pathologic findings with potential clinical relevance, a systematic review of the CT scans appears mandatory.


8 citations in Web of Science®
8 citations in Scopus®
Google Scholar™



1 download since deposited on 18 Aug 2009
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Nuclear Medicine
04 Faculty of Medicine > Center for Integrative Human Physiology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Date:December 2009
Deposited On:18 Aug 2009 13:09
Last Modified:05 Apr 2016 13:19
Additional Information:The original publication is available at www.springerlink.com
Publisher DOI:10.1007/s10554-009-9490-x
PubMed ID:19662511

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page