Quick Search:

uzh logo
Browse by:

Zurich Open Repository and Archive

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-20281

Franke, S; Ibarra, F; Schulz, C M; Twele, R; Poldy, J; Barrow, R A; Peakall, R; Schiestl, F P; Francke, W (2009). The discovery of 2,5-dialkylcyclohexan-1,3-diones as a new class of natural products. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106(22):8877-8882.

[img] PDF - Registered users only
View at publisher


Orchids employing sexual deceit attract males of their pollinator species through specific volatile signals that mimic female-released sex pheromones. One of these signals proved to be 2-ethyl-5-propylcyclohexan-1,3-dione (chiloglottone1), a new natural product that was shown to be most important in the relations between orchids of the genus Chiloglottis, native to Australia, and corresponding pollinator species. Systematic investigations on the mass spectrometric fragmentation pattern of 2,5-dialkylcyclohexan-1,3-diones identified key ions providing information about the structures of the substituents at positions 2 and 5. Results enabled us to identify 2-ethyl-5-pentylcyclohexan-1,3-dione (chiloglottone2) and 2-butyl-5-methylcyclohexan-1,3-dione (chiloglottone3) as new natural products that play a decisive role in the pollination syndrome of some Chiloglottis species. During field bioassays, pure synthetic samples of chiloglottone1-3 or mixtures thereof proved to be attractive to the corresponding orchid pollinators. Because of their likely biogenesis from ubiquitous fatty acid precursors, 2,5-dialkylcyclohexan-1,3-diones may represent a hitherto overlooked, widespread class of natural products.


41 citations in Web of Science®
40 citations in Scopus®
Google Scholar™



1 download since deposited on 19 Aug 2009
0 downloads since 12 months

Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Systematic Botany and Botanical Gardens
Dewey Decimal Classification:580 Plants (Botany)
Deposited On:19 Aug 2009 13:33
Last Modified:05 Apr 2016 13:19
Publisher:National Academy of Sciences
Additional Information:Copyright: National Academy of Sciences USA
Publisher DOI:10.1073/pnas.0900646106
Official URL:http://www.pnas.org
PubMed ID:19470640

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page