Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-20337
Pluta, R M; Hansen-Schwartz, J; Dreier, J; Vajkoczy, P; Macdonald, R L; Nishizawa, S; Kasuya, H; Wellmann, G; Keller, E; Zauner, A; Dorsch, N; Clark, J; Ono, S; Kiris, T; Leroux, P; Zhang, J H (2009). Cerebral vasospasm following subarachnoid hemorrhage: time for a new world of thought. Neurological Research, 31(2):151-158.
View at publisher
Objective: Delayed cerebral vasospasm has long been recog-nized as an important cause of poor outcome after an otherwise successful treatment of a ruptured intracranial aneurysm, but it remains a pathophysiological enigma despite intensive research for more than half a century.
Method: Summarized in this review are highlights of research from North America, Europe and Asia reflecting recent advances in the understanding of delayed ischemic deficit.
Result: It will focus on current accepted mechanisms and on new frontiers in vasospasm research.
Conclusion: A key issue is the recognition of events other than arterial narrowing such as early brain injury and cortical spreading depression and of their contribution to overall mortality and morbidity.
355 downloads since deposited on 25 Aug 2009
179 downloads since 12 months
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurosurgery|
|Dewey Decimal Classification:||610 Medicine & health|
|Deposited On:||25 Aug 2009 08:59|
|Last Modified:||27 Nov 2013 18:58|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page