Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-20337
Pluta, R M; Hansen-Schwartz, J; Dreier, J; Vajkoczy, P; Macdonald, R L; Nishizawa, S; Kasuya, H; Wellmann, G; Keller, E; Zauner, A; Dorsch, N; Clark, J; Ono, S; Kiris, T; Leroux, P; Zhang, J H (2009). Cerebral vasospasm following subarachnoid hemorrhage: time for a new world of thought. Neurological Research, 31(2):151-158.
Objective: Delayed cerebral vasospasm has long been recog-nized as an important cause of poor outcome after an otherwise successful treatment of a ruptured intracranial aneurysm, but it remains a pathophysiological enigma despite intensive research for more than half a century.
Method: Summarized in this review are highlights of research from North America, Europe and Asia reflecting recent advances in the understanding of delayed ischemic deficit.
Result: It will focus on current accepted mechanisms and on new frontiers in vasospasm research.
Conclusion: A key issue is the recognition of events other than arterial narrowing such as early brain injury and cortical spreading depression and of their contribution to overall mortality and morbidity.
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurosurgery|
|DDC:||610 Medicine & health|
|Deposited On:||25 Aug 2009 08:59|
|Last Modified:||27 Nov 2013 18:58|
|Citations:||Web of Science®. Times Cited: 112|
Scopus®. Citation Count: 135
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