Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive

Johnston, L A; Gallant, P (2002). Control of growth and organ size in Drosophila. BioEssays, 24(1):54-64.

Full text not available from this repository.

View at publisher

Abstract

Transplantation experiments have shown that developing metazoan organs carry intrinsic information about their size and shape. Organ and body size are also sensitive to extrinsic cues provided by the environment, such as the availability of nutrients. The genetic and molecular pathways that contribute to animal size and shape are numerous, yet how they cooperate to control growth is mysterious. The recent identification and characterization of several mutations affecting growth in Drosophila melanogaster promises to provide insights. Many of these mutations affect the extrinsic control of animal size; others affect the organ-intrinsic control of pattern and size. In this review, we summarize the characteristics of some of these mutations and their roles in growth and size control. In addition, we speculate about possible connections between the extrinsic and intrinsic pathways controlling growth and pattern.

Citations

108 citations in Web of Science®
111 citations in Scopus®
Google Scholar™

Altmetrics

Additional indexing

Item Type:Journal Article, refereed
Communities & Collections:07 Faculty of Science > Institute of Zoology (former)
DDC:570 Life sciences; biology
590 Animals (Zoology)
Language:English
Date:1 January 2002
Deposited On:11 Feb 2008 12:13
Last Modified:27 Nov 2013 19:51
Publisher:Wiley-Blackwell
ISSN:0265-9247
Publisher DOI:10.1002/bies.10021
PubMed ID:11782950

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page