Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-23920
Trenkmann, M; Brock, M; Ospelt, C; Gay, S (2010). Epigenetics in Rheumatoid Arthritis. Clinical Reviews in Allergy and Immunology, 39(1):10-19.
View at publisher
Epigenetics is a steadily growing research area. In many human diseases, especially in cancers, but also in autoimmune diseases, epigenetic aberrations have been found. Rheumatoid arthritis is an autoimmune disease characterized by chronic inflammation and destruction of synovial joints. Even though the etiology is not yet fully understood, rheumatoid arthritis is generally considered to be caused by a combination of genetic predisposition, deregulated immunomodulation, and environmental influences. To gain a better understanding of this disease, researchers have become interested in studying epigenetic changes in rheumatoid arthritis. Here, we want to review the current knowledge on epigenetics in rheumatoid arthritis.
324 downloads since deposited on 11 Nov 2009
10 downloads since 12 months
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > Center for Integrative Human Physiology
04 Faculty of Medicine > University Hospital Zurich > Rheumatology Clinic and Institute of Physical Medicine
|Dewey Decimal Classification:||570 Life sciences; biology
610 Medicine & health
|Deposited On:||11 Nov 2009 14:18|
|Last Modified:||27 Nov 2013 17:05|
|Additional Information:||The original publication is available at www.springerlink.com|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page