Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-24013
Soellinger, M; Rutz, A K; Kozerke, S; Boesiger, P (2009). 3D cine displacement-encoded MRI of pulsatile brain motion. Magnetic Resonance in Medicine, 61(1):153-162.
- Registered users only
View at publisher
Pulsatile brain motion is considered to be an important mechanical link between blood and cerebrospinal fluid (CSF) dynamics. Like many severe brain diseases, different types of hydrocephalus are associated with impairment of these dynamics. In this work a cine displacement-encoded imaging method employing stimulated echoes (DENSE) and a three-dimensional (3D) segmented echo-planar imaging (EPI) readout for brain motion measurements in all three spatial directions is presented. Displacement-encoded data sets of 12 healthy volunteers were analyzed with respect to reproducibility, periodicity, and intra- as well as intersubject physiological consistency. In addition, displacement values were compared with data derived from phase-contrast (PC) velocity measurements in a subset of all measured subjects. Using DENSE, displacements as low as 0.01 mm could be detected and observation of the 3D pulse pressure wave propagation was possible. Among other parameters, peak displacements in the central brain regions were measured: feet–head (FH): thalamus (0.13 ± 0.01 mm); right–left (RL): thalamus (0.06 ± 0.01 mm); and anterior–posterior (AP): caudate nucleus (0.05 ± 0.01 mm).
1 download since deposited on 02 Dec 2009
0 downloads since 12 months
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > Institute of Biomedical Engineering|
|Dewey Decimal Classification:||170 Ethics
610 Medicine & health
|Deposited On:||02 Dec 2009 16:08|
|Last Modified:||18 Feb 2013 10:14|
Users (please log in): suggest update or correction for this item
Repository Staff Only: item control page