Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-24480
Brenni, M; Worn, M; Brüesch, M; Spahn, D R; Ganter, M (2010). Successful rotational thromboelastometry-guided treatment of traumatic haemorrhage, hyperfibrinolysis and coagulopathy. Acta Anaesthesiologica Scandinavica, 54(1):111-117.
PDF (Accepted mansucript)
Transfusion of allogeneic blood products is associated with increased morbidity and mortality. Therefore, strategies for reducing transfusion of these products during trauma management are valuable. We report a case of severe blunt abdominal trauma, successfully treated with antifibrinolytic medication and fibrinogen concentrate. Rotational thromboelastometry (ROTEM) was used to identify hyperfibrinolysis and afibrinogenaemia. In order to achieve haemostasis, over a 3-h period, the patient received a total of 1 g of tranexamic acid, 7 U of packed red blood cells, 16 g of fibrinogen concentrate (Haemocomplettan P), 3500 ml of colloids and 5500 ml of lactated Ringer's solution. Together with surgical measures, this treatment stopped the bleeding and stabilised the patient. There was no transfusion of either fresh-frozen plasma or platelets. The limited need for allogeneic blood products is of particular interest, and clinical studies of the approach used here appear to be warranted.
|Item Type:||Journal Article, refereed, further contribution|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Institute of Anesthesiology|
|DDC:||610 Medicine & health|
|Uncontrolled Keywords:||case report|
|Deposited On:||30 Nov 2009 08:42|
|Last Modified:||27 Nov 2013 21:11|
|Citations:||Web of Science®. Times Cited: 36|
Scopus®. Citation Count: 37
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