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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-24964

Pizza, F; Biallas, M; Wolf, M; Valko, P O; Bassetti, C L (2009). Periodic leg movements during sleep and cerebral hemodynamic changes detected by NIRS. Clinical Neurophysiology, 120(7):1329-1334.

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OBJECTIVE: Periodic leg movements during sleep (PLMS) have been shown to be associated with changes in autonomic and hemispheric activities. Near infrared spectroscopy (NIRS) assesses hemodynamic changes linked to hemispheric/cortical activity. We applied NIRS to test whether cerebral hemodynamic alterations accompany PLMS. METHODS: Three PLMS patients underwent nocturnal polysomnography coupled with cerebral NIRS. EEG correlates of PLMS were scored and NIRS data were analysed for the identification of correspondent hemodynamic changes. RESULTS: PLMS were constantly associated with cerebral hemodynamic fluctuations that showed greater amplitude when associated to changes in EEG and were present also in absence of any visually detectable arousal or A phase in the EEG. CONCLUSION: This is the first study documenting cerebral hemodynamic changes linked to PLMS. SIGNIFICANCE: The clinical relevance of these observations remains to be determined.


4 citations in Web of Science®
4 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology
Dewey Decimal Classification:610 Medicine & health
Deposited On:02 Dec 2009 08:50
Last Modified:05 Apr 2016 13:36
Publisher DOI:10.1016/j.clinph.2009.05.009
PubMed ID:19540159

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