Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-24964
Pizza, F; Biallas, M; Wolf, M; Valko, P O; Bassetti, C L (2009). Periodic leg movements during sleep and cerebral hemodynamic changes detected by NIRS. Clinical Neurophysiology, 120(7):1329-1334.
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OBJECTIVE: Periodic leg movements during sleep (PLMS) have been shown to be associated with changes in autonomic and hemispheric activities. Near infrared spectroscopy (NIRS) assesses hemodynamic changes linked to hemispheric/cortical activity. We applied NIRS to test whether cerebral hemodynamic alterations accompany PLMS. METHODS: Three PLMS patients underwent nocturnal polysomnography coupled with cerebral NIRS. EEG correlates of PLMS were scored and NIRS data were analysed for the identification of correspondent hemodynamic changes. RESULTS: PLMS were constantly associated with cerebral hemodynamic fluctuations that showed greater amplitude when associated to changes in EEG and were present also in absence of any visually detectable arousal or A phase in the EEG. CONCLUSION: This is the first study documenting cerebral hemodynamic changes linked to PLMS. SIGNIFICANCE: The clinical relevance of these observations remains to be determined.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Neurology
|DDC:||610 Medicine & health|
|Deposited On:||02 Dec 2009 08:50|
|Last Modified:||27 Nov 2013 16:47|
|Citations:||Web of Science®. Times Cited: 4|
Scopus®. Citation Count: 3
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