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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-25627

Brauchlin, A E; Rudiger, A; Bächli, E B; Schmid, C; Maggiorini, M (2009). Portal vein thrombus and liver failure in a patient with pheochromocytoma crisis. American Journal of Emergency Medicine, 27(5):630.e3-630.e5.

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A 51-year-old man with known pheochromocytoma refused surgical treatment over several years and subsequently presented in catecholamine crisis with shock and multiple organ failure. Laboratory testing revealed liver failure with elevated liver enzymes and coagulation abnormalities, and imaging showed ischemia of extended parts of the right liver lobe. It also revealed a large thrombus in the right portal vein, which together with severe arterial vasoconstriction impaired the dual blood supply of the liver. The patient recovered after effective medical treatment and finally underwent surgical tumor resection. Thereafter, antihypertensive treatment could be stopped. We present this exceptional case of adrenal crisis and discuss the mechanisms leading to liver failure in general and portal vein thrombosis in particular.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic and Policlinic for Internal Medicine
04 Faculty of Medicine > University Hospital Zurich > Clinic for Endocrinology and Diabetology
DDC:610 Medicine & health
Deposited On:04 Jan 2010 09:55
Last Modified:27 Nov 2013 23:19
Publisher DOI:10.1016/j.ajem.2008.09.002
PubMed ID:19497483
Citations:Web of Science®. Times Cited: 3
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Scopus®. Citation Count: 4

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