Quick Search:

uzh logo
Browse by:
bullet
bullet
bullet
bullet

Zurich Open Repository and Archive 

Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-26197

Greutmann, M; Prêtre, René; Furrer, L; Bauersfeld, U; Turina, M; Noll, G; Luescher, T F; Trindade, P T (2009). Heart transplantation in adolescent and adult patients with congenital heart disease: a case-control study. Transplantation Proceedings, 41(9):3821-3826.

[img] PDF - Registered users only
149kB

Abstract

BACKGROUND: The number of adolescent and adult patients with congenital heart disease undergoing heart transplantation is increasing. We aimed to better define
the characteristics of these patients and their survival after transplantation.
METHODS: We describe a group of patients with end-stage heart failure owing to congenital heart disease undergoing heart transplantation at a single tertiary center and compare their short- and long-term survival with a group of matched controls with dilated cardiomyopathy and the entire cohort of transplanted patients at our center. RESULTS: Between 1985 and 2006, a total of 322 orthotopic heart transplantations were performed at our center. Thirteen patients (mean age, 27.5 years) had a diagnosis of congenital heart disease with a wide spectrum of lesions. The survival of these 13 patients was 85% at 30 days, 1, 5, and 10 years and 77% at 20 years, which did not differ significantly to the short- and long-term survival of the entire cohort of patients with heart transplantation and to the survival of age-matched controls with dilated cardiomyopathy.
CONCLUSION: In our single-center experience, short- and long-term survival after heart transplantation in a selected, small group of patients with end-stage heart
failure owing to congenital heart disease did not differ significantly compared with a group of age-matched controls and the entire cohort.

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiovascular Surgery
04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
DDC:610 Medicine & health
Language:English
Date:November 2009
Deposited On:21 Dec 2009 12:49
Last Modified:06 Dec 2013 15:36
Publisher:Elsevier
ISSN:0041-1345
Publisher DOI:10.1016/j.transproceed.2009.06.198
PubMed ID:19917394
Citations:Web of Science®. Times Cited: 5
Google Scholar™
Scopus®. Citation Count: 7

Users (please log in): suggest update or correction for this item

Repository Staff Only: item control page