Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-26197
Greutmann, M; Prêtre, René; Furrer, L; Bauersfeld, U; Turina, M; Noll, G; Luescher, T F; Trindade, P T (2009). Heart transplantation in adolescent and adult patients with congenital heart disease: a case-control study. Transplantation Proceedings, 41(9):3821-3826.
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BACKGROUND: The number of adolescent and adult patients with congenital heart disease undergoing heart transplantation is increasing. We aimed to better define
the characteristics of these patients and their survival after transplantation.
METHODS: We describe a group of patients with end-stage heart failure owing to congenital heart disease undergoing heart transplantation at a single tertiary center and compare their short- and long-term survival with a group of matched controls with dilated cardiomyopathy and the entire cohort of transplanted patients at our center. RESULTS: Between 1985 and 2006, a total of 322 orthotopic heart transplantations were performed at our center. Thirteen patients (mean age, 27.5 years) had a diagnosis of congenital heart disease with a wide spectrum of lesions. The survival of these 13 patients was 85% at 30 days, 1, 5, and 10 years and 77% at 20 years, which did not differ significantly to the short- and long-term survival of the entire cohort of patients with heart transplantation and to the survival of age-matched controls with dilated cardiomyopathy.
CONCLUSION: In our single-center experience, short- and long-term survival after heart transplantation in a selected, small group of patients with end-stage heart
failure owing to congenital heart disease did not differ significantly compared with a group of age-matched controls and the entire cohort.
|Item Type:||Journal Article, refereed, original work|
|Communities & Collections:||04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiology|
04 Faculty of Medicine > University Hospital Zurich > Clinic for Cardiovascular Surgery
04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
|DDC:||610 Medicine & health|
|Deposited On:||21 Dec 2009 13:49|
|Last Modified:||23 Dec 2012 18:57|
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