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Biosensing by densely packed and optically coupled plasmonic particle arrays


Sannomiya, T; Sahoo, P K; Mahcicek, D I; Solak, H H; Hafner, C; Grieshaber, D; Vörös, J (2009). Biosensing by densely packed and optically coupled plasmonic particle arrays. Small, 5(16):1889-1896.

Abstract

Densely packed plasmonic particle arrays are investigated for biosensing applications. Such particle arrays exhibit interparticle optical coupling creating a strong field between the particles, which is useful for sensing purposes. The sensor properties, such as bulk sensitivity, layer sensitivity, and the depth of sensitivity are investigated with the aid of a multiple multipole program. Sensitivity to the analyte with low concentration is also examined by a dynamic adsorption processes. The detectable concentration limit of streptavidin within 3000 s in the detection system is expected from the signal-to-noise to be less than 150 pM.

Densely packed plasmonic particle arrays are investigated for biosensing applications. Such particle arrays exhibit interparticle optical coupling creating a strong field between the particles, which is useful for sensing purposes. The sensor properties, such as bulk sensitivity, layer sensitivity, and the depth of sensitivity are investigated with the aid of a multiple multipole program. Sensitivity to the analyte with low concentration is also examined by a dynamic adsorption processes. The detectable concentration limit of streptavidin within 3000 s in the detection system is expected from the signal-to-noise to be less than 150 pM.

Citations

35 citations in Web of Science®
33 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Language:English
Date:2009
Deposited On:22 Dec 2009 14:17
Last Modified:05 Apr 2016 13:41
Publisher:Wiley-Blackwell
ISSN:1613-6810
Additional Information:The definitive version is available at www.blackwell-synergy.com
Publisher DOI:10.1002/smll.200900284
PubMed ID:19384877

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