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Pregnancy-associated glycoproteins as a new diagnostic tool in cattle reproduction


Gajewski, Z; Pertajtis, M; Sousa, N M; Beckers, J F; Pawlinski, B; Janett, F (2009). Pregnancy-associated glycoproteins as a new diagnostic tool in cattle reproduction. Schweizer Archiv für Tierheilkunde, 151(12):577-582.

Abstract

Pregnancy-associated glycoproteins (PAGs) are powerful pregnancy markers in domestic cattle. These proteins are expressed in mono- and binucleate trophoblast cells from the first days of gestation until calving. Different molecules were identified as being expressed at various stages of pregnancy. However, up to date, their functions and activities during pregnancy were not yet established. Specific RIA tests were developed (classic and alternative RIA) and used to measure the concentration of these glycoproteins in blood during gestation and the postpartum period in cattle. In maternal blood, PAGs rise to detectable levels from days 24 to 28 after fertilization. A recent study indicated that PAGs can also be detected in milk samples. However, concentrations in milk are much lower when compared to those of plasma.

Pregnancy-associated glycoproteins (PAGs) are powerful pregnancy markers in domestic cattle. These proteins are expressed in mono- and binucleate trophoblast cells from the first days of gestation until calving. Different molecules were identified as being expressed at various stages of pregnancy. However, up to date, their functions and activities during pregnancy were not yet established. Specific RIA tests were developed (classic and alternative RIA) and used to measure the concentration of these glycoproteins in blood during gestation and the postpartum period in cattle. In maternal blood, PAGs rise to detectable levels from days 24 to 28 after fertilization. A recent study indicated that PAGs can also be detected in milk samples. However, concentrations in milk are much lower when compared to those of plasma.

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Additional indexing

Other titles:Trächtigkeits-assozierte Glykoproteine als neues Diagnostikum in der Rinderzucht
Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Farm Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:2009
Deposited On:07 Jan 2010 14:46
Last Modified:05 Apr 2016 13:41
Publisher:Hans Huber
ISSN:0036-7281
Additional Information:This article does not exactly replicate the final version published in Schweizer Archiv für Tierheilkunde'. It is not a copy of the original published article and is not suitable for citation.
Publisher DOI:10.1024/0036-7281.151.12.577
PubMed ID:19946848
Permanent URL: http://doi.org/10.5167/uzh-26382

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