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In vitro model of a semicircular canal: Design and validation of the model and its use for the study of canalithiasis


Obrist, D; Hegemann, S; Kronenberg, D; Häuselmann, O; Rösgen, T (2010). In vitro model of a semicircular canal: Design and validation of the model and its use for the study of canalithiasis. Journal of Biomechanics, 43(6):1208-1214.

Abstract

We present an experimental model for a semicircular canal with canalithiasis. Canalithiasis is a pathological condition where free-floating particles disturb the flow field in the semicircular canals. It may lead to a specific form of vertigo known as BPPV or top-shelf vertigo. A careful scaling of the physical and geometrical parameters allows us to study the mechanics of this disease on an enlarged model of a single semicircular canal with laser vibrometry and video particle tracking. Early results confirm the proper operation of the model canal and support the current theories on the mechanisms of BPPV.

We present an experimental model for a semicircular canal with canalithiasis. Canalithiasis is a pathological condition where free-floating particles disturb the flow field in the semicircular canals. It may lead to a specific form of vertigo known as BPPV or top-shelf vertigo. A careful scaling of the physical and geometrical parameters allows us to study the mechanics of this disease on an enlarged model of a single semicircular canal with laser vibrometry and video particle tracking. Early results confirm the proper operation of the model canal and support the current theories on the mechanisms of BPPV.

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9 citations in Web of Science®
7 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Otorhinolaryngology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:19 April 2010
Deposited On:06 Jan 2010 08:34
Last Modified:05 Apr 2016 13:42
Publisher:Elsevier
ISSN:0021-9290
Publisher DOI:https://doi.org/10.1016/j.jbiomech.2009.11.027
PubMed ID:20035941
Permanent URL: https://doi.org/10.5167/uzh-26756

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